3-Amino-N-cyclopropylbenzamide hydrochloride

3-Amino-N-cyclopropylbenzamide hydrochloride is a halo entry in the catalogue: CAS 871673-24-4, C10H12N2O, packed in 1kg / 25kg / 100kg.

On an sp3 carbon the halide competes between substitution and elimination, so the temperature of the step decides the outcome more than the leaving group does. The ring constrains the geometry of the fragment, so the entry is bought for the shape it imposes on the rest of the molecule rather than for a single reactive site. The salt form is chosen for handling and storage; the free base or free acid is generated in situ when the reaction needs it.

The formula C10H12N2O resolves to 10 carbons with one oxygen and 2 nitrogens. At 10 carbons the entry is an oil or a low-melting solid, and it is handled at ambient temperature in most steps.

Handling and storage

Keep in the dark and closed; the alcohol that forms on hydrolysis is the impurity that appears first.

Ordering

Quoted from stock in 1kg / 25kg / 100kg, or made to order where the lot has run down. Either way the same release testing applies. Where a specification has to be met on paper before shipment, it is agreed in writing and the lot is qualified against it rather than against the catalogue text.