Terminal Alkynes
Terminal alkynes with the C-H free at one end: the entry point for Sonogashira coupling, copper-catalysed azide-alkyne cycloaddition, and metalation followed by trapping with an electrophile. The alkynes in this group carry a second functional group – a hydroxyl, an acid, an ester or a protected amine – because that is what makes them a building block rather than a reagent. Chain lengths run from C4 to C16, so the same chemistry can be run on a short tether or on a long lipophilic chain.
| CAS | Compound | Formula | MW | Packing | Quote |
|---|---|---|---|---|---|
| 764-93-2 | 1-Decyne | C10H18 | 138.25 | 1kg / 25kg / 100kg | Request |
| 17356-19-3 | 1-Ethynylcyclopentanol | C7H10O | 110.15 | 1kg / 25kg / 100kg | Request |
| 491862-64-7 | 1-Methyl-2-propyn-1-yl 5-hexynoate | C10H12O2 | 164.20 | 1kg / 25kg / 100kg | Request |
| 818-72-4 | 1-Octyn-3-ol | C8H14O | 126.20 | 1kg / 25kg / 100kg | Request |
| 4187-86-4 | 1-Pentyn-3-ol | C5H8O | 84.12 | 1kg / 25kg / 100kg | Request |
| 622-76-4 | 1-Phenyl-1-butyne | C10H10 | 130.19 | 1kg / 25kg / 100kg | Request |
| 18202-10-3 | 11-Dodecyn-1-ol | C12H22O | 182.30 | 1kg / 25kg / 100kg | Request |
| 65686-49-9 | 11-Hexadecyn-1-ol | C16H30O | 238.41 | 1kg / 25kg / 100kg | Request |
| 18202-11-4 | 12-Tridecyn-1-ol | C13H24O | 196.33 | 1kg / 25kg / 100kg | Request |
| 18202-12-5 | 13-Tetradecyn-1-ol | C14H26O | 210.36 | 1kg / 25kg / 100kg | Request |
| 20739-58-6 | 2-Octyn-1-ol | C8H14O | 126.20 | 1kg / 25kg / 100kg | Request |
| 927-74-2 | 3-Butyn-1-ol | C4H6O | 70.09 | 1kg / 25kg / 100kg | Request |
| 41143-12-8 | 4-Hexynoic acid | C6H8O2 | 112.13 | 1kg / 25kg / 100kg | Request |
| 6089-09-4 | 4-Pentynoic acid | C5H6O2 | 98.10 | 1kg / 25kg / 100kg | Request |
| 21565-82-2 | 4-Pentynoic acid, methyl ester | C6H8O2 | 112.13 | 1kg / 25kg / 100kg | Request |
| 74149-25-0 | 4,4-diethoxybut-2-ynal | C8H12O3 | 156.18 | 1kg / 25kg / 100kg | Request |
| 928-90-5 | 5-Hexyn-1-ol | C6H10O | 98.14 | 1kg / 25kg / 100kg | Request |
| 53293-00-8 | 5-Hexynoic acid | C6H8O2 | 112.13 | 1kg / 25kg / 100kg | Request |
| 108545-38-6 | 5-Hexynoic acid, ethyl ester | C8H12O2 | 140.18 | 1kg / 25kg / 100kg | Request |
| 30964-00-2 | 6-Heptynoic acid | C7H10O2 | 126.15 | 1kg / 25kg / 100kg | Request |
| 63478-76-2 | 6-Heptynoic alcohol | C7H12O | 112.17 | 1kg / 25kg / 100kg | Request |
| 41862-94-6 | 7-Dodecyn-1-ol | C12H22O | 182.30 | 1kg / 25kg / 100kg | Request |
| 871-91-0 | 7-Octyn-1-ol | C8H14O | 126.20 | 1kg / 25kg / 100kg | Request |
| 10160-28-8 | 8-Nonyn-1-ol | C9H16O | 140.22 | 1kg / 25kg / 100kg | Request |
| 60037-69-6 | 9-Tetradecyn-1-ol | C14H26O | 210.36 | 1kg / 25kg / 100kg | Request |
| 4039-82-1 | Benzyl propargyl ether | C10H10O | 146.19 | 1kg / 25kg / 100kg | Request |
| 5390-04-5 | Pent-4-yn-1-ol | C5H8O | 84.12 | 1kg / 25kg / 100kg | Request |
Terminal Alkynes outside the catalogue
If the compound you need is not in this group but belongs to it chemically, send the structure. Most of what we make is not on the site: the catalogue is the part that is already characterised and packed.
A route review costs nothing and usually comes back within two working days with the step count and the likely purification burden.
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Group: Terminal Alkynes