1-Ethynylcyclopentanol

1-Ethynylcyclopentanol (CAS 17356-19-3) is a C7H10O alkyne building block supplied in kilogram lots.

Because the alkyne hydrogen is acidic enough to deprotonate cleanly, this entry is usually the nucleophile in whichever step it appears in. The ring constrains the geometry of the fragment, so the entry is bought for the shape it imposes on the rest of the molecule rather than for a single reactive site.

The formula C7H10O resolves to 7 carbons with one oxygen. A 7-carbon chain sits between volatility and lipophilicity, which is the range most often used when a fragment has to stay in the organic phase without being waxy.

Handling and storage

Alkynes are held closed, dry and out of direct light; the silylated entries are also moisture sensitive and are packed under inert gas.

Ordering

The unit weights held are 1kg / 25kg / 100kg. A split shipment across two of those sizes is treated as one lot and one certificate. Where a specification has to be met on paper before shipment, it is agreed in writing and the lot is qualified against it rather than against the catalogue text.