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4,4-diethoxybut-2-ynal

CAS 74149-25-0 C8H12O3 156.18 g/mol Catalogue item Terminal Alkynes
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Structure of 4,4-diethoxybut-2-ynal, CAS 74149-25-0
Structure · C8H12O3
CAS number
74149-25-0
Molecular formula
C8H12O3
Molecular weight
156.18 g/mol
Standard packing
1kg / 25kg / 100kg

4,4-diethoxybut-2-ynal (CAS 74149-25-0) is an aldehyde building block of formula C8H12O3, supplied in kilogram lots.

The aldehyde carbon is electrophilic, so reductive amination, Wittig olefination and aldol addition are the usual entry points into a route. The acetal is a masked carbonyl. It survives base and hydride conditions and is opened under acid, which is what makes it useful in the middle of a sequence.

The formula C8H12O3 resolves to 8 carbons with 3 oxygens. A 8-carbon chain sits between volatility and lipophilicity, which is the range most often used when a fragment has to stay in the organic phase without being waxy.

Handling and storage

Aldehydes oxidise in air. The container is kept closed with a small headspace, and the lot is used soon after opening.

Ordering

Supplied in 1kg / 25kg / 100kg; a gram-scale sample is quoted against the same specification, so the analysis seen at sample stage is the analysis of the kilo lot.

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Entry4,4-diethoxybut-2-ynal
CAS74149-25-0
Typical lead timeStock or 2–4 weeks
DocumentationCOA, SDS, spec sheet

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4,4-diethoxybut-2-ynal (74149-25-0)

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