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16-Hexadecanolide

CAS 109-29-5 C16H30O2 254.41 g/mol Catalogue item Acids, Esters & Lactones
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Structure of 16-Hexadecanolide, CAS 109-29-5
Structure · C16H30O2
CAS number
109-29-5
Molecular formula
C16H30O2
Molecular weight
254.41 g/mol
Standard packing
1kg / 25kg / 100kg

CAS 109-29-5, 16-Hexadecanolide, is a lactone building block (C16H30O2) whose ring is opened or carried through as the route requires.

Macrocyclic lactones of this size are closed in dilute solution, so residual solvent and the grade of the lot matter as much as the assay.

The formula C16H30O2 resolves to 16 carbons with 2 oxygens. With 16 carbons the lipophilicity dominates: solubility in polar media falls away and the work-up is usually a phase separation.

Where this entry sits in a route

16-Hexadecanolide is a macrocyclic lactone, the ring-closed form of 16-hydroxyhexadecanoic acid. It is bought as a fragrance material and as a monomer for ring-opening polymerisation, and both uses depend on the same property: the ring is strained enough to open cleanly but stable enough to store.

What the analysis covers

The lot is checked for the open-chain hydroxy acid and for residual catalyst from the cyclisation. The hydroxy acid is the impurity that matters, because it changes both the odour profile and the polymerisation behaviour.

Handling and storage

Store closed and dry, and check the residual hydroxy acid if the container has been open for a while.

Ordering

Packing 1kg / 25kg / 100kg, with the batch COA, the SDS and a specification sheet suitable for incoming inspection travelling with the lot.

Quotation questions for this entry

What is the difference between the lactone and the hydroxy acid?

They are the closed and open forms of the same molecule. The lactone is the storage form; the hydroxy acid is what appears when the ring is opened by base or by moisture.

Is it used as a fragrance material?

Yes, and as a monomer. Both uses are supported by the same specification, which is why the residual hydroxy acid is controlled.

How is it packed?

1 kg, 25 kg and 100 kg. The material is warmed before packing so that the unit weight is accurate.

Can it be polymerised directly?

Ring-opening polymerisation is the usual route, with a metal or organocatalyst. The water content of the lot has to be controlled because it acts as a chain transfer agent.

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Quotation

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Entry16-Hexadecanolide
CAS109-29-5
Typical lead timeStock or 2–4 weeks
DocumentationCOA, SDS, spec sheet

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16-Hexadecanolide (109-29-5)

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